Treatment Resistant Depression (TRD)

TRD occurs in individuals suffering from major depression who fail to respond to initial antidepressant treatments. AXS-05 is a novel, oral, investigational drug product, incorporating multiple mechanisms of action, under development for the treatment of TRD and Alzheimer’s disease agitation.

Learn more about TRD and AXS-05


Knee OA Associated with Bone Marrow Lesions (BMLs)

Knee OA is a disorder characterized by bone changes around the knee joint, progressive loss of joint cartilage, joint space narrowing, and eventual total joint failure. Knee OA results in knee pain, significant physical disability, and reduced quality of life.

Learn more about Knee OA and AXS-02